This is a tough one, I'll try to answer in the context of: how useful is this synthesizer if the display and all indicator LEDs were broken?
The fun can be split up into two parts I think:
The first part is just playing the instrument. There's a keyboard, a mod wheel, pitch bend, so nothing new here. The sliders and knobs allow you to alterate the patch in some ways. The knobs at the top right for effects (I wish it was assignable to other functions though). All these things you can do without the neccity of vision. Patches can be assigned to the 16 sequencer buttons as shortcuts. So for this part you would be just fine.
The other part is in making patches. This is where it probably gets very difficult. Parameters of the operators (envelopes, wave shapes and such) are 'hidden' under the buttons (which are pretty small by itself already). So could you press the button for Level and adjust the envelope using the knobs? Well yes, but under this button are multiple pages with further settings. By pressing the Level (for example) button again, you cycle through the pages. The page you were on is remembered. So switching from the Pitch settings back to Level settings does not bring you to page 1 of the Level settings. Without a visual aid, I think it would be challenging to know on what page you are, as the result of turning the knobs isn't always clearly audible.
Also, since it has six operators, these settings are per operator. The "OP Select" buttons switch between them, where 6 LEDs indicate which one is active. Once again; without vision hard to tell which one is active. The top-right knobs are just very contextual.
So for the second part, creating patches, I would not recommend this device. I suppose you would find yourself lost in a maze, to find out what affects what.
Considering the above, I think you would have to decide whether it's worth the price tag. Personally, if I would only be able to use patches of others, it would take away a big part of the fun. In exploration, one finds out that FM can be unpredictable and has a lot of possibilities. It does come with complexity, way more than a subtractive synthesizer. Therefore there's not really another way than to put settings under menus, other than having hardware knobs for each (significant) setting.
Okay, the "Look Mum No Computer"s Sega Megadrive controller is an exception here. But that's a museum piece
